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GNA11 mutations in 1 cancer type possibly contribute to the detection of the gene in the PAN-cancer anlaysis:: Stomach adenocarcinoma

GNA11
Ensembl id ENSG00000088256
Mutated samples
Coding Sequence 20 (0.3%)
Protein Affecting 16 (0.2%)
Mode of action Activating
Known driver Yes
Cancer type Signals (Biases)
PAN
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all GNA11 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Stomach adenocarcinoma Yes 2 2 1.24
Cutaneous melanoma No 9 7 1.90
Uterine corpus endometrioid carcinoma No 2 2 0.87
Lung adenocarcinoma No 1 1 0.26
Lung squamous cell carcinoma No 1 1 0.57
Serous ovarian adenocarcinoma No 1 1 0.32
Colorectal adenocarcinoma No 2 1 0.44
Glioblastoma multiforme No 1 1 0.26
Renal clear cell carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence