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FCRL4 is detected as a mutational cancer driver in 1 cancer type: Cutaneous melanoma

FCRL4
Ensembl id ENSG00000163518
Mutated samples
Coding Sequence 85 (1.3%)
Protein Affecting 65 (1.0%)
Mode of action Unclassified
Known driver Yes
Cancer type Signals (Biases)
CM C
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FCRL4 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma Yes 27 19 5.15
Head and neck squamous cell carcinoma No 13 12 3.20
Lung adenocarcinoma No 8 7 1.79
Stomach adenocarcinoma No 7 5 3.11
Renal clear cell carcinoma No 4 4 0.96
Small cell lung carcinoma No 3 3 4.35
Prostate adenocarcinoma No 3 2 0.82
Breast carcinoma No 3 2 0.17
Lung squamous cell carcinoma No 5 2 1.15
Serous ovarian adenocarcinoma No 2 2 0.63
Colorectal adenocarcinoma No 2 2 0.87
Glioblastoma multiforme No 2 2 0.53
Bladder carcinoma No 1 1 1.02
Esophageal carcinoma No 2 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Medulloblastoma No 1 0 0.00
Uterine corpus endometrioid carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence