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FBXO38 has not been detected as a mutational cancer driver

FBXO38
Ensembl id ENSG00000145868
Mutated samples
Coding Sequence 67 (1.0%)
Protein Affecting 43 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all FBXO38 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 12 9 2.44
Lung adenocarcinoma No 10 7 1.79
Serous ovarian adenocarcinoma No 5 5 1.58
Head and neck squamous cell carcinoma No 4 3 0.80
Glioblastoma multiforme No 6 3 0.79
Prostate adenocarcinoma No 2 2 0.82
Bladder carcinoma No 2 2 2.04
Breast carcinoma No 4 2 0.17
Stomach adenocarcinoma No 4 2 1.24
Small cell lung carcinoma No 2 2 2.90
Colorectal adenocarcinoma No 5 2 0.87
Renal clear cell carcinoma No 4 1 0.24
Uterine corpus endometrioid carcinoma No 2 1 0.43
Esophageal carcinoma No 1 1 0.68
Acute lymphocytic leukemia No 1 1 0.82
Hepatocarcinoma No 1 0 0.00
Lung squamous cell carcinoma No 1 0 0.00
Lower grade glioma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence