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FAT1 × Pancreatic Adenocarcinoma ×

FAT1 is detected as a mutational cancer driver in Pancreatic Adenocarcinoma

FAT1 reports in Pancreatic Adenocarcinoma (PAAD)

Cancer type details
Pancreatic Adenocarcinoma
Cohorts 7
Samples 922
Mutations 2,520,434
Driver genes 64
Gene details
FAT1
Ensembl ID ENSG00000083857
Transcript ID ENST00000441802
Protein ID ENSP00000406229
Cohorts where is driver 2
Mutated samples 8
Mutated samples (%) 0.87
Mutations 22
Mode of action Activating
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence