IntOGen - FAS gene cancer mutations

FAS is detected as a mutational cancer driver

FAS reports

Methods
Mutation distribution

Gene details

FAS
Gene ID ENSG00000026103 Transcript ID ENST00000652046 Protein ID ENSP00000498466
Cancer types where is driver 3 Cohorts where is driver 3 Mutated samples 15 Mutations 142
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence