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EZH2 × Acute Myeloid Leukemia ×

EZH2 is detected as a mutational cancer driver in Acute Myeloid Leukemia

EZH2 reports in Acute Myeloid Leukemia (AML)

Cancer type details
Acute Myeloid Leukemia
Cohorts 9
Samples 661
Mutations 295,755
Driver genes 62
Gene details
EZH2
Ensembl ID ENSG00000106462
Transcript ID ENST00000320356
Protein ID ENSP00000320147
Cohorts where is driver 3
Mutated samples 12
Mutated samples (%) 1.82
Mutations 18
Mode of action Ambiguous
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence