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EYS has not been detected as a mutational cancer driver

EYS
Ensembl id ENSG00000188107
Mutated samples
Coding Sequence 205 (3.0%)
Protein Affecting 131 (1.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all EYS gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 20 17 4.35
Breast carcinoma No 18 16 1.39
Cutaneous melanoma No 24 15 4.07
Head and neck squamous cell carcinoma No 17 14 3.73
Lung squamous cell carcinoma No 13 13 7.47
Uterine corpus endometrioid carcinoma No 16 13 5.65
Esophageal carcinoma No 14 13 8.90
Renal clear cell carcinoma No 8 7 1.68
Small cell lung carcinoma No 6 6 8.70
Stomach adenocarcinoma No 7 5 3.11
Hepatocarcinoma No 8 3 3.33
Colorectal adenocarcinoma No 3 3 1.31
Prostate adenocarcinoma No 3 2 0.82
Bladder carcinoma No 1 1 1.02
Serous ovarian adenocarcinoma No 1 1 0.32
Diffuse B cell lymphoma No 4 1 4.35
Glioblastoma multiforme No 1 1 0.26
Pancreas adenocarcinoma No 1 0 0.00
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 24 0 0.00
Pylocytic astrocytoma No 13 0 0.00
Acute lymphocytic leukemia No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence