Top
ETV6 has not been detected as a mutational cancer driver

ETV6
Ensembl id ENSG00000139083
Mutated samples
Coding Sequence 55 (0.8%)
Protein Affecting 40 (0.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ETV6 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 14 13 3.52
Head and neck squamous cell carcinoma No 5 5 1.33
Lung adenocarcinoma No 4 3 0.77
Lung squamous cell carcinoma No 4 3 1.72
Stomach adenocarcinoma No 4 3 1.86
Bladder carcinoma No 2 2 2.04
Acute myeloid leukemia No 2 2 1.02
Breast carcinoma No 2 2 0.17
Hepatocarcinoma No 2 1 1.11
Pancreas adenocarcinoma No 1 1 0.47
Renal clear cell carcinoma No 1 1 0.24
Uterine corpus endometrioid carcinoma No 2 1 0.43
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Esophageal carcinoma No 1 1 0.68
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 5 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence