IntOGen - ELN gene cancer mutations

ELN is detected as a mutational cancer driver

ELN reports

Methods
Mutation distribution

Gene details

ELN
Gene ID ENSG00000049540 Transcript ID ENST00000252034 Protein ID ENSP00000252034
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 18 Mutations 383
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence