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DNMT3A is detected as a mutational cancer driver

DNMT3A reports

Gene details
DNMT3A
Ensembl ID ENSG00000119772
Transcript ID ENST00000264709
Protein ID ENSP00000264709
Cancer types where is driver 7
Cohorts where is driver 11
Mutated samples 89
Mutations 383
Mode of action Loss of function
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence