DHX40 has not been detected as a mutational cancer driver

Ensembl id ENSG00000108406
Mutated samples
Coding Sequence 32 (0.5%)
Protein Affecting 22 (0.3%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all DHX40 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 12 7 1.90
Uterine corpus endometrioid carcinoma No 5 4 1.74
Stomach adenocarcinoma No 4 3 1.86
Prostate adenocarcinoma No 2 2 0.82
Breast carcinoma No 2 2 0.17
Small cell lung carcinoma No 2 2 2.90
Lung adenocarcinoma No 1 1 0.26
Glioblastoma multiforme No 1 1 0.26
Renal clear cell carcinoma No 2 0 0.00
Colorectal adenocarcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence