IntOGen - DDB2 gene cancer mutations

DDB2 is detected as a mutational cancer driver

DDB2 reports

Methods
Mutation distribution

Gene details

DDB2
Ensembl ID ENSG00000134574 Transcript ID ENST00000256996 Protein ID ENSP00000256996
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 5 Mutations 118
Mode of action Ambiguous
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence