IntOGen - CSF1R gene cancer mutations

CSF1R is detected as a mutational cancer driver

CSF1R reports

Methods
Mutation distribution

Gene details

CSF1R
Ensembl ID ENSG00000182578 Transcript ID ENST00000286301 Protein ID ENSP00000286301
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 5 Mutations 414
Mode of action Loss of function
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence