Top
CD2AP has not been detected as a mutational cancer driver

CD2AP
Ensembl id ENSG00000198087
Mutated samples
Coding Sequence 43 (0.6%)
Protein Affecting 27 (0.4%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CD2AP gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 16 9 2.44
Head and neck squamous cell carcinoma No 6 5 1.33
Lung adenocarcinoma No 2 2 0.51
Bladder carcinoma No 2 2 2.04
Renal clear cell carcinoma No 2 2 0.48
Stomach adenocarcinoma No 4 2 1.24
Serous ovarian adenocarcinoma No 1 1 0.32
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 2 1 0.44
Glioblastoma multiforme No 2 1 0.26
Esophageal carcinoma No 1 1 0.68
Hepatocarcinoma No 2 0 0.00
Medulloblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence