IntOGen - CARD11 gene cancer mutations

CARD11 is detected as a mutational cancer driver

CARD11 reports

Methods
Mutation distribution

Gene details

CARD11
Ensembl ID ENSG00000198286 Transcript ID ENST00000396946 Protein ID ENSP00000380150
Cancer types where is driver 8 Cohorts where is driver 12 Mutated samples 90 Mutations 971
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence