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CACNA1G has not been detected as a mutational cancer driver

CACNA1G
Ensembl id ENSG00000006283
Mutated samples
Coding Sequence 161 (2.4%)
Protein Affecting 108 (1.6%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CACNA1G gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 50 31 8.40
Lung adenocarcinoma No 13 9 2.30
Head and neck squamous cell carcinoma No 11 9 2.40
Renal clear cell carcinoma No 9 8 1.92
Uterine corpus endometrioid carcinoma No 11 8 3.48
Breast carcinoma No 13 7 0.61
Lung squamous cell carcinoma No 8 6 3.45
Stomach adenocarcinoma No 10 6 3.73
Bladder carcinoma No 6 5 5.10
Esophageal carcinoma No 6 5 3.42
Thyroid carcinoma No 3 2 0.62
Lower grade glioma No 5 2 1.18
Serous ovarian adenocarcinoma No 2 2 0.63
Hepatocarcinoma No 1 1 1.11
Acute myeloid leukemia No 2 1 0.51
Medulloblastoma No 1 1 0.48
Chronic lymphocytic leukemia No 2 1 0.34
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 1 1 0.44
Diffuse B cell lymphoma No 1 1 4.35
Glioblastoma multiforme No 2 1 0.26
Prostate adenocarcinoma No 2 0 0.00
Acute lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence