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CA10 has not been detected as a mutational cancer driver

CA10
Ensembl id ENSG00000154975
Mutated samples
Coding Sequence 84 (1.2%)
Protein Affecting 47 (0.7%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all CA10 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 22 14 3.79
Lung squamous cell carcinoma No 7 5 2.87
Lung adenocarcinoma No 6 4 1.02
Head and neck squamous cell carcinoma No 5 4 1.07
Renal clear cell carcinoma No 4 3 0.72
Bladder carcinoma No 2 2 2.04
Stomach adenocarcinoma No 5 2 1.24
Small cell lung carcinoma No 4 2 2.90
Colorectal adenocarcinoma No 2 2 0.87
Esophageal carcinoma No 2 2 1.37
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 2 1 1.11
Neuroblastoma No 1 1 0.48
Uterine corpus endometrioid carcinoma No 3 1 0.43
Chronic lymphocytic leukemia No 12 1 0.34
Multiple myeloma No 1 1 1.45
Serous ovarian adenocarcinoma No 1 1 0.32
Pylocytic astrocytoma No 3 0 0.00
Diffuse B cell lymphoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence