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AUTS2 has not been detected as a mutational cancer driver

AUTS2
Ensembl id ENSG00000158321
Mutated samples
Coding Sequence 124 (1.8%)
Protein Affecting 66 (1.0%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all AUTS2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Stomach adenocarcinoma No 16 13 8.07
Cutaneous melanoma No 26 10 2.71
Lung adenocarcinoma No 9 8 2.05
Head and neck squamous cell carcinoma No 11 7 1.87
Bladder carcinoma No 5 4 4.08
Breast carcinoma No 7 4 0.35
Uterine corpus endometrioid carcinoma No 6 4 1.74
Esophageal carcinoma No 5 4 2.74
Serous ovarian adenocarcinoma No 4 2 0.63
Glioblastoma multiforme No 2 2 0.53
Prostate adenocarcinoma No 2 1 0.41
Medulloblastoma No 1 1 0.48
Lung squamous cell carcinoma No 4 1 0.57
Renal clear cell carcinoma No 3 1 0.24
Multiple myeloma No 1 1 1.45
Lower grade glioma No 1 1 0.59
Small cell lung carcinoma No 1 1 1.45
Colorectal adenocarcinoma No 3 1 0.44
Hepatocarcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 7 0 0.00
Pylocytic astrocytoma No 9 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence