IntOGen - ATR gene cancer mutations

ATR is detected as a mutational cancer driver

ATR reports

Methods
Mutation distribution

Gene details

ATR
Gene ID ENSG00000175054 Transcript ID ENST00000350721 Protein ID ENSP00000343741
Cancer types where is driver 4 Cohorts where is driver 4 Mutated samples 12 Mutations 900
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence