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ATPAF2 has not been detected as a mutational cancer driver

ATPAF2
Ensembl id ENSG00000171953
Mutated samples
Coding Sequence 50 (0.7%)
Protein Affecting 12 (0.2%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ATPAF2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Renal clear cell carcinoma No 4 3 0.72
Cutaneous melanoma No 13 3 0.81
Head and neck squamous cell carcinoma No 5 2 0.53
Bladder carcinoma No 4 1 1.02
Breast carcinoma No 1 1 0.09
Uterine corpus endometrioid carcinoma No 3 1 0.43
Stomach adenocarcinoma No 8 1 0.62
Lung adenocarcinoma No 2 0 0.00
Hepatocarcinoma No 1 0 0.00
Lung squamous cell carcinoma No 3 0 0.00
Pancreas adenocarcinoma No 1 0 0.00
Neuroblastoma No 1 0 0.00
Glioblastoma multiforme No 2 0 0.00
Esophageal carcinoma No 2 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence