IntOGen - ARHGEF10 gene cancer mutations

ARHGEF10 is detected as a mutational cancer driver

ARHGEF10 reports

Methods
Mutation distribution

Gene details

ARHGEF10
Gene ID ENSG00000104728 Transcript ID ENST00000349830 Protein ID ENSP00000340297
Cancer types where is driver 4 Cohorts where is driver 4 Mutated samples 22 Mutations 412
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence