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ARHGEF10 is detected as a mutational cancer driver

ARHGEF10 reports

Gene details
ARHGEF10
Ensembl ID ENSG00000104728
Transcript ID ENST00000518288
Protein ID ENSP00000431012
Cancer types where is driver 4
Cohorts where is driver 4
Mutated samples 21
Mutations 339
Mode of action Ambiguous
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Mutation distribution
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence