ARFGAP3 is detected as a mutational cancer driver in 1 cancer type: Prostate adenocarcinoma

Ensembl id ENSG00000242247
Mutated samples
Coding Sequence 36 (0.5%)
Protein Affecting 26 (0.4%)
Mode of action Loss of function
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ARFGAP3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Prostate adenocarcinoma Yes 5 5 2.06
Cutaneous melanoma No 12 8 2.17
Breast carcinoma No 4 4 0.35
Stomach adenocarcinoma No 4 3 1.86
Lung adenocarcinoma No 2 2 0.51
Bladder carcinoma No 2 2 2.04
Hepatocarcinoma No 2 1 1.11
Head and neck squamous cell carcinoma No 1 1 0.27
Non small cell lung carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
Pylocytic astrocytoma No 1 0 0.00
Esophageal carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence