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ANGPT1 has not been detected as a mutational cancer driver

ANGPT1
Ensembl id ENSG00000154188
Mutated samples
Coding Sequence 111 (1.6%)
Protein Affecting 75 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ANGPT1 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 46 37 10.03
Lung adenocarcinoma No 10 7 1.79
Stomach adenocarcinoma No 6 4 2.48
Breast carcinoma No 6 3 0.26
Renal clear cell carcinoma No 3 3 0.72
Serous ovarian adenocarcinoma No 4 3 0.95
Colorectal adenocarcinoma No 4 3 1.31
Head and neck squamous cell carcinoma No 4 3 0.80
Esophageal carcinoma No 6 3 2.05
Uterine corpus endometrioid carcinoma No 2 2 0.87
Small cell lung carcinoma No 2 2 2.90
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 2 1 1.11
Lung squamous cell carcinoma No 3 1 0.57
Non small cell lung carcinoma No 1 1 3.23
Glioblastoma multiforme No 2 1 0.26
Chronic lymphocytic leukemia No 8 0 0.00
Pylocytic astrocytoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence