IntOGen - AFDN gene cancer mutations

AFDN is detected as a mutational cancer driver

AFDN reports

Methods
Mutation distribution

Gene details

AFDN
Gene ID ENSG00000130396 Transcript ID ENST00000683244 Protein ID ENSP00000507324
Cancer types where is driver 2 Cohorts where is driver 3 Mutated samples 25 Mutations 595
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence