Top
ABCA3 has not been detected as a mutational cancer driver

ABCA3
Ensembl id ENSG00000167972
Mutated samples
Coding Sequence 127 (1.9%)
Protein Affecting 77 (1.1%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all ABCA3 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Cutaneous melanoma No 48 25 6.78
Stomach adenocarcinoma No 9 9 5.59
Breast carcinoma No 13 7 0.61
Lung adenocarcinoma No 8 5 1.28
Uterine corpus endometrioid carcinoma No 5 5 2.17
Lung squamous cell carcinoma No 9 4 2.30
Renal clear cell carcinoma No 4 4 0.96
Serous ovarian adenocarcinoma No 5 4 1.27
Head and neck squamous cell carcinoma No 8 3 0.80
Esophageal carcinoma No 3 3 2.05
Thyroid carcinoma No 5 2 0.62
Prostate adenocarcinoma No 1 1 0.41
Hepatocarcinoma No 2 1 1.11
Medulloblastoma No 1 1 0.48
Non small cell lung carcinoma No 2 1 3.23
Colorectal adenocarcinoma No 1 1 0.44
Glioblastoma multiforme No 1 1 0.26
Bladder carcinoma No 1 0 0.00
Chronic lymphocytic leukemia No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence