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BRCA2 × Invasive Breast Carcinoma ×

BRCA2 is detected as a mutational cancer driver in Invasive Breast Carcinoma

BRCA2 reports in Invasive Breast Carcinoma (BRCA)

Cancer type details
Invasive Breast Carcinoma
Cohorts 14
Samples 3,227
Mutations 20,232,318
Driver genes 118
Gene details
BRCA2
Gene ID ENSG00000139618
Transcript ID ENST00000380152
Protein ID ENSP00000369497
Cohorts where is driver 2
Mutated samples 24
Mutated samples (%) 0.74
Mutations 74
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence