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165 mutational cancer drivers have been detected in this of Stomach adenocarcinoma (STAD) project from The Cancer Genome Atlas. The most mutated drivers are: TP53, ARID1A, PIK3CA, APC, ACVR2A, etc.



Stomach cancer TCGA obtained from Synapse
STAD Stomach adenocarcinoma
139 Samples
Driver / Mut. genes165 / 20578
The Cancer Genome Atlas
Coding sequence mutations (CSMs)
in driver genes 951
in all genes 69273
Protein affecting mutations (PAMs)
in driver genes 779
in all genes 33488
This driver cloud represents the most recurrently mutated cancer driver genes in the Stomach cancer TCGA obtained from Synapse dataset. The size of the gene symbol is relative to the count of samples with PAMs.
This plot shows the most recurrently mutated cancer driver genes in the Stomach cancer TCGA obtained from Synapse dataset. Each bar of the histogram indicates the amount of samples with PAMs.

Gene symbol Ensembl id Driver class Mutated samples % Mutated samples
TP53 ENSG00000141510 63 62 44.60
ARID1A ENSG00000117713 22 22 15.83
PIK3CA ENSG00000121879 21 21 15.11
APC ENSG00000134982 16 14 10.07
ACVR2A ENSG00000121989 14 14 10.07
SMAD4 ENSG00000141646 12 9 6.47
MYH9 ENSG00000100345 13 12 8.63
KRAS ENSG00000133703 12 12 8.63
RHOA ENSG00000067560 10 7 5.04
CTNNB1 ENSG00000168036 9 8 5.76
BCOR ENSG00000183337 9 9 6.47
SMARCA4 ENSG00000127616 10 8 5.76
PTPRU ENSG00000060656 9 9 6.47
HLA-B ENSG00000234745 7 7 5.04
PCSK5 ENSG00000099139 8 8 5.76
RASA1 ENSG00000145715 7 7 5.04
STARD13 ENSG00000133121 7 7 5.04
CAD ENSG00000084774 8 7 5.04
RPL22 ENSG00000116251 7 6 4.32
TNPO2 ENSG00000105576 7 7 5.04
IRF2 ENSG00000168310 7 7 5.04
RBBP7 ENSG00000102054 6 6 4.32
SMAD2 ENSG00000175387 5 5 3.60
HLA-A ENSG00000206503 5 5 3.60
EPHA1 ENSG00000146904 6 6 4.32
PIK3R1 ENSG00000145675 6 6 4.32
PTPRF ENSG00000142949 6 6 4.32
CAT ENSG00000121691 11 3 2.16
ATRX ENSG00000085224 9 5 3.60
CNOT1 ENSG00000125107 7 3 2.16
NUP107 ENSG00000111581 7 4 2.88
EIF4G1 ENSG00000114867 8 4 2.88
LPHN2 ENSG00000117114 9 5 3.60
NSD1 ENSG00000165671 7 4 2.88
TAOK2 ENSG00000149930 7 3 2.16
BRCA1 ENSG00000012048 7 5 3.60
EGFR ENSG00000146648 7 4 2.88
MED12 ENSG00000184634 7 5 3.60
CHEK2 ENSG00000183765 7 5 3.60
SRGAP3 ENSG00000196220 6 5 3.60
TJP1 ENSG00000104067 5 4 2.88
MKL1 ENSG00000196588 7 3 2.16
AQR ENSG00000021776 6 4 2.88
NCKAP1 ENSG00000061676 7 5 3.60
NUP98 ENSG00000110713 7 5 3.60
EIF2AK3 ENSG00000172071 6 5 3.60
CLTC ENSG00000141367 5 2 1.44
ATIC ENSG00000138363 6 5 3.60
ERBB2IP ENSG00000112851 4 4 2.88
SETD2 ENSG00000181555 6 5 3.60
CEP290 ENSG00000198707 6 5 3.60
FGFR2 ENSG00000066468 6 5 3.60
CDC73 ENSG00000134371 6 2 1.44
MSR1 ENSG00000038945 6 5 3.60
BPTF ENSG00000171634 6 4 2.88
ARHGAP35 ENSG00000160007 6 4 2.88
DHX15 ENSG00000109606 5 3 2.16
CHD1L ENSG00000131778 6 5 3.60
GATA3 ENSG00000107485 5 2 1.44
ARHGEF6 ENSG00000129675 6 5 3.60
CYLD ENSG00000083799 6 4 2.88
CASP8 ENSG00000064012 6 5 3.60
TCF7L2 ENSG00000148737 5 4 2.88
MAP3K1 ENSG00000095015 5 4 2.88
MECOM ENSG00000085276 5 4 2.88
HNRPDL ENSG00000152795 5 5 3.60
IREB2 ENSG00000136381 4 4 2.88
BAP1 ENSG00000163930 5 3 2.16
DLG1 ENSG00000075711 5 4 2.88
CUL1 ENSG00000055130 4 4 2.88
KDM6A ENSG00000147050 5 5 3.60
CLASP2 ENSG00000163539 4 3 2.16
CCT5 ENSG00000150753 5 3 2.16
DDX5 ENSG00000108654 4 3 2.16
ELF3 ENSG00000163435 5 4 2.88
FOXP1 ENSG00000114861 4 4 2.88
ATR ENSG00000175054 5 4 2.88
SIN3A ENSG00000169375 5 5 3.60
COL1A1 ENSG00000108821 5 4 2.88
THRAP3 ENSG00000054118 4 4 2.88
NR4A2 ENSG00000153234 5 3 2.16
TP53BP1 ENSG00000067369 5 4 2.88
FUBP1 ENSG00000162613 5 5 3.60
ZMYM2 ENSG00000121741 3 2 1.44
ACVR1B ENSG00000135503 4 4 2.88
AFF4 ENSG00000072364 5 3 2.16
ARHGAP26 ENSG00000145819 4 4 2.88
CDKN2A ENSG00000147889 4 3 2.16
CNOT4 ENSG00000080802 5 2 1.44
CUL3 ENSG00000036257 4 4 2.88
POLR2B ENSG00000047315 3 2 1.44
TCF4 ENSG00000196628 4 4 2.88
BRAF ENSG00000157764 4 4 2.88
PTPN11 ENSG00000179295 4 4 2.88
GNAI1 ENSG00000127955 4 3 2.16
MLH1 ENSG00000076242 4 2 1.44
MED17 ENSG00000042429 4 3 2.16
SOS2 ENSG00000100485 4 2 1.44
DNMT3A ENSG00000119772 4 4 2.88
SOX9 ENSG00000125398 3 3 2.16
MYH11 ENSG00000133392 4 3 2.16
CSDA ENSG00000060138 4 4 2.88
MAP2K4 ENSG00000065559 3 3 2.16
MET ENSG00000105976 4 3 2.16
ACSL6 ENSG00000164398 3 2 1.44
TJP2 ENSG00000119139 4 4 2.88
SMC1A ENSG00000072501 4 4 2.88
EEF1A1 ENSG00000156508 4 3 2.16
FAM123B ENSG00000184675 4 4 2.88
NCK1 ENSG00000158092 4 4 2.88
TAF1 ENSG00000147133 3 3 2.16
NAP1L1 ENSG00000187109 3 3 2.16
CLOCK ENSG00000134852 2 2 1.44
STIP1 ENSG00000168439 3 3 2.16
TBL1XR1 ENSG00000177565 3 3 2.16
RUNX1 ENSG00000159216 3 2 1.44
TBX3 ENSG00000135111 3 3 2.16
IRS2 ENSG00000185950 3 3 2.16
TFDP1 ENSG00000198176 3 3 2.16
KLF4 ENSG00000136826 3 3 2.16
PRRX1 ENSG00000116132 3 3 2.16
PIK3CB ENSG00000051382 3 3 2.16
CAPN7 ENSG00000131375 3 3 2.16
DIS3 ENSG00000083520 3 2 1.44
ZC3H11A ENSG00000058673 3 2 1.44
CSDE1 ENSG00000009307 3 2 1.44
G3BP2 ENSG00000138757 3 2 1.44
SUZ12 ENSG00000178691 3 3 2.16
SPOP ENSG00000121067 2 2 1.44
CCAR1 ENSG00000060339 3 2 1.44
ACTG2 ENSG00000163017 3 3 2.16
PPP2R1A ENSG00000105568 3 2 1.44
WIPF1 ENSG00000115935 3 3 2.16
ERCC2 ENSG00000104884 3 3 2.16
NFE2L2 ENSG00000116044 2 2 1.44
PIP5K1A ENSG00000143398 3 2 1.44
CUL2 ENSG00000108094 3 3 2.16
EIF4A2 ENSG00000156976 3 2 1.44
MAP2K1 ENSG00000169032 3 2 1.44
ACAD8 ENSG00000151498 3 2 1.44
SF3B1 ENSG00000115524 3 3 2.16
RBM5 ENSG00000003756 2 2 1.44
LCP1 ENSG00000136167 2 2 1.44
EZH2 ENSG00000106462 2 2 1.44
STK4 ENSG00000101109 2 2 1.44
ATP6AP2 ENSG00000182220 2 2 1.44
FLT3 ENSG00000122025 2 2 1.44
NEDD4L ENSG00000049759 2 2 1.44
GOLGA5 ENSG00000066455 2 2 1.44
RTN4 ENSG00000115310 2 2 1.44
SOS1 ENSG00000115904 2 2 1.44
GNA11 ENSG00000088256 2 2 1.44
KLF6 ENSG00000067082 2 2 1.44
ADAM10 ENSG00000137845 2 2 1.44
CSNK1G3 ENSG00000151292 2 2 1.44
COPS2 ENSG00000166200 2 2 1.44
TNPO1 ENSG00000083312 2 2 1.44
PHF6 ENSG00000156531 2 2 1.44
NR2F2 ENSG00000185551 2 2 1.44
HSP90AB1 ENSG00000096384 2 2 1.44
RAD21 ENSG00000164754 2 2 1.44
PTGS1 ENSG00000095303 2 2 1.44
WT1 ENSG00000184937 2 2 1.44
HDAC3 ENSG00000171720 2 2 1.44
FAS ENSG00000026103 2 2 1.44