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2 mutational cancer drivers have been detected in this of Pylocytic astrocytoma (PA) project from Sanger Institute. The most mutated drivers are: FGFR1, PTPN11, etc.



Pilocytic Astrocytoma New Samples obtained from AlexandrovEtAl
PA Pylocytic astrocytoma
63 Samples
Driver / Mut. genes2 / 4461
Sanger Institute
doi:10.1038/nature12477
Coding sequence mutations (CSMs)
in driver genes 8
in all genes 6002
Protein affecting mutations (PAMs)
in driver genes 7
in all genes 91
This driver cloud represents the most recurrently mutated cancer driver genes in the Pilocytic Astrocytoma New Samples obtained from AlexandrovEtAl dataset. The size of the gene symbol is relative to the count of samples with PAMs.
This plot shows the most recurrently mutated cancer driver genes in the Pilocytic Astrocytoma New Samples obtained from AlexandrovEtAl dataset. Each bar of the histogram indicates the amount of samples with PAMs.

Gene symbol Ensembl id Driver class Mutated samples % Mutated samples
FGFR1 ENSG00000077782 5 4 6.35
PTPN11 ENSG00000179295 2 2 3.17