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5 mutational cancer drivers have been detected in this of Hepatocarcinoma (HC) project from International Agency for Cancer Research. The most mutated drivers are: CTNNB1, ARID1A, NFE2L2, NFATC4, BLM, etc.



Liver cancer IARC
HC Hepatocarcinoma
24 Samples
Driver / Mut. genes5 / 1180
International Agency for Cancer Research
PMID:22561517
Coding sequence mutations (CSMs)
in driver genes 19
in all genes 1264
Protein affecting mutations (PAMs)
in driver genes 19
in all genes 898
This driver cloud represents the most recurrently mutated cancer driver genes in the Liver cancer IARC dataset. The size of the gene symbol is relative to the count of samples with PAMs.
This plot shows the most recurrently mutated cancer driver genes in the Liver cancer IARC dataset. Each bar of the histogram indicates the amount of samples with PAMs.

Gene symbol Ensembl id Driver class Mutated samples % Mutated samples
CTNNB1 ENSG00000168036 9 9 37.50
ARID1A ENSG00000117713 3 3 12.50
NFE2L2 ENSG00000116044 3 3 12.50
NFATC4 ENSG00000100968 2 2 8.33
BLM ENSG00000197299 2 2 8.33