MAX is detected as a mutational cancer driver in 1 Lower grade glioma project

Lower grade glioma
Projects 1
169 Samples
Coding sequence mutations (CSMs)
in driver genes 595
in all genes 11911
Protein affecting mutations (PAMs)
in driver genes 566
in all genes 5986
Ensembl id ENSG00000125952
Mutated samples
Coding Sequence 3 (1.8%)
Protein Affecting 3 (1.8%)
Mode of action Activating
Known driver No
Project Signals
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated Lower grade glioma projects in all MAX gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Project Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Low Grade Glioma TCGA Yes 3 3 1.78
The mutations needle plot shows the distribution of the observed MAX cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence Driver classification