FAT3 is detected as a mutational cancer driver in Invasive Breast Carcinoma

FAT3 reports in Invasive Breast Carcinoma (BRCA)

Cancer type details
Invasive Breast Carcinoma
Cohorts 14
Samples 3,201
Mutations 19,887,724
Driver genes 117
Gene details
Ensembl ID ENSG00000165323
Transcript ID ENST00000409404
Protein ID ENSP00000387040
Cohorts where is driver 3
Mutated samples 46
Mutated samples (%) 1.44
Mutations 133
Mode of action Ambiguous
Known driver True
Method signals per Cohort
Cohort Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Samples (%) Consequence