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AKAP2 has not been detected as a mutational cancer driver

AKAP2
Ensembl id ENSG00000241978
Mutated samples
Coding Sequence 121 (1.8%)
Protein Affecting 60 (0.9%)
Mode of action Unclassified
Known driver No
Cancer type Signals (Biases)
Clust Clustered Mutations FM Functional Mutations Rec Recurrent Mutations
This plot shows the most recurrently mutated cancer types in all AKAP2 gene mutations. Each bar of the histogram indicates the amount of samples with PAMs.

Cancer type Driver Mutated samples (CS) Mutated samples (PAM) % Mutated samples (PAM)
Lung adenocarcinoma No 11 7 1.79
Head and neck squamous cell carcinoma No 14 7 1.87
Cutaneous melanoma No 18 6 1.63
Breast carcinoma No 9 5 0.44
Uterine corpus endometrioid carcinoma No 6 5 2.17
Stomach adenocarcinoma No 8 5 3.11
Glioblastoma multiforme No 6 5 1.32
Lung squamous cell carcinoma No 5 4 2.30
Renal clear cell carcinoma No 7 3 0.72
Serous ovarian adenocarcinoma No 4 3 0.95
Bladder carcinoma No 2 2 2.04
Colorectal adenocarcinoma No 6 2 0.87
Esophageal carcinoma No 3 2 1.37
Prostate adenocarcinoma No 1 1 0.41
Pancreas adenocarcinoma No 1 1 0.47
Non small cell lung carcinoma No 2 1 3.23
Diffuse B cell lymphoma No 1 1 4.35
Hepatocarcinoma No 4 0 0.00
Thyroid carcinoma No 3 0 0.00
Neuroblastoma No 1 0 0.00
Chronic lymphocytic leukemia No 4 0 0.00
Lower grade glioma No 1 0 0.00
Pylocytic astrocytoma No 3 0 0.00
Small cell lung carcinoma No 1 0 0.00
The mutations needle plot shows the distribution of the observed cancer mutations along the protein sequence and it's possible mutational clusters and hotspots. The needles' height and head size represent mutational recurrence. Needles of different categories that fall in the same amino acid residues are stacked.

Variant Locus Samples AA pos AA change Consequence