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TGFBR2 is detected as a mutational cancer driver

TGFBR2 reports

Gene details
TGFBR2
Ensembl ID ENSG00000163513
Transcript ID ENST00000359013
Protein ID ENSP00000351905
Cancer types where is driver 6
Cohorts where is driver 10
Mutated samples 70
Mutations 270
Mode of action Loss of function
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence