IntOGen - STAG2 gene cancer mutations

STAG2 is detected as a mutational cancer driver

STAG2 reports

Methods
Mutation distribution

Gene details

STAG2
Ensembl ID ENSG00000101972 Transcript ID ENST00000218089 Protein ID ENSP00000218089
Cancer types where is driver 11 Cohorts where is driver 17 Mutated samples 155 Mutations 460
Mode of action Loss of function
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence