IntOGen - SIN3A gene cancer mutations

SIN3A is detected as a mutational cancer driver

SIN3A reports

Methods
Mutation distribution

Gene details

SIN3A
Ensembl ID ENSG00000169375 Transcript ID ENST00000394947 Protein ID ENSP00000378402
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 3 Mutations 506
Mode of action Loss of function
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence