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SETDB1 is detected as a mutational cancer driver

SETDB1 reports

Gene details
SETDB1
Ensembl ID ENSG00000143379
Transcript ID ENST00000271640
Protein ID ENSP00000271640
Cancer types where is driver 3
Cohorts where is driver 3
Mutated samples 16
Mutations 331
Mode of action Activating
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence