RB1 is detected as a mutational cancer driver
RB1 reports
Gene details
RB1 |
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Ensembl ID
ENSG00000139687
Transcript ID ENST00000267163 Protein ID ENSP00000267163 |
Cancer types where is driver
24
Cohorts where is driver 52 Mutated samples 566 Mutations 850 |
Mode of action Loss of function |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
BLCA (Bladder cancer) | 113 | 92 | 81.42 |
NSCLC (Non-small cell lung cancer) | 79 | 55 | 69.62 |
SCLC (Small-cell lung cancer) | 100 | 88 | 88.00 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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