IntOGen - PPP6C gene cancer mutations

PPP6C is detected as a mutational cancer driver

PPP6C reports

Methods
Mutation distribution

Gene details

PPP6C
Ensembl ID ENSG00000119414 Transcript ID ENST00000451402 Protein ID ENSP00000392147
Cancer types where is driver 2 Cohorts where is driver 5 Mutated samples 75 Mutations 181
Mode of action Ambiguous
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence