IntOGen - PIK3CB gene cancer mutations

PIK3CB is detected as a mutational cancer driver

PIK3CB reports

Methods
Mutation distribution

Gene details

PIK3CB
Ensembl ID ENSG00000051382 Transcript ID ENST00000289153 Protein ID ENSP00000289153
Cancer types where is driver 3 Cohorts where is driver 5 Mutated samples 29 Mutations 299
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence