PBRM1 is detected as a mutational cancer driver
PBRM1 reports
Gene details
PBRM1 |
---|
Ensembl ID
ENSG00000163939
Transcript ID ENST00000394830 Protein ID ENSP00000378307 |
Cancer types where is driver
8
Cohorts where is driver 13 Mutated samples 228 Mutations 567 |
Mode of action Loss of function |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
---|
In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
R (Kidney cancer) | 8 | 6 | 75.00 |
RCCC (Renal clear cell carcinoma) | 118 | 102 | 86.44 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
---|