IntOGen - MTOR gene cancer mutations

MTOR is detected as a mutational cancer driver

MTOR reports

Methods
Mutation distribution

Gene details

MTOR
Ensembl ID ENSG00000198793 Transcript ID ENST00000361445 Protein ID ENSP00000354558
Cancer types where is driver 11 Cohorts where is driver 15 Mutated samples 127 Mutations 638
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence