IntOGen - MGA gene cancer mutations

MGA is detected as a mutational cancer driver

MGA reports

Methods
Mutation distribution

Gene details

MGA
Ensembl ID ENSG00000174197 Transcript ID ENST00000219905 Protein ID ENSP00000219905
Cancer types where is driver 5 Cohorts where is driver 5 Mutated samples 85 Mutations 1,037
Mode of action Loss of function
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence