KRAS is detected as a mutational cancer driver
KRAS reports
Gene details
KRAS |
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Ensembl ID
ENSG00000133703
Transcript ID ENST00000256078 Protein ID ENSP00000256078 |
Cancer types where is driver
29
Cohorts where is driver 68 Mutated samples 2,234 Mutations 2,378 |
Mode of action Activating |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
COREAD (Colorectal adenocarcinoma) | 77 | 71 | 92.21 |
L (Lymphoid cancer) | 7 | 5 | 71.43 |
LK (Leukemia) | 44 | 42 | 95.45 |
LUAD (Lung adenocarcinoma) | 25 | 23 | 92.00 |
LUNG_CANCER (Lung cancer) | 1 | 0 | 0.00 |
MM (Multiple myeloma) | 61 | 56 | 91.80 |
NSCLC (Non-small cell lung cancer) | 19 | 10 | 52.63 |
PA (Pancreatic cancer) | 2 | 0 | 0.00 |
PAAD (Pancreas adenocarcinoma) | 53 | 50 | 94.34 |
UCEC (Endometrial cancer) | 19 | 15 | 78.95 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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