IntOGen - INPPL1 gene cancer mutations

INPPL1 is detected as a mutational cancer driver

INPPL1 reports

Methods
Mutation distribution

Gene details

INPPL1
Ensembl ID ENSG00000165458 Transcript ID ENST00000298229 Protein ID ENSP00000298229
Cancer types where is driver 1 Cohorts where is driver 1 Mutated samples 22 Mutations 577
Mode of action Loss of function
Known driver False

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence