IDH1 is detected as a mutational cancer driver
IDH1 reports
Gene details
IDH1 |
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Ensembl ID
ENSG00000138413
Transcript ID ENST00000415913 Protein ID ENSP00000390265 |
Cancer types where is driver
13
Cohorts where is driver 27 Mutated samples 654 Mutations 782 |
Mode of action Activating |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
CNS (Central nervous system cancer) | 4 | 4 | 100.00 |
G (Glioma) | 14 | 14 | 100.00 |
LGG (Lower grade glioma) | 7 | 7 | 100.00 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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