IntOGen - GNA11 gene cancer mutations

GNA11 is detected as a mutational cancer driver

GNA11 reports

Methods
Mutation distribution

Gene details

GNA11
Ensembl ID ENSG00000088256 Transcript ID ENST00000078429 Protein ID ENSP00000078429
Cancer types where is driver 2 Cohorts where is driver 3 Mutated samples 48 Mutations 129
Mode of action Activating
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence