FOXA1 is detected as a mutational cancer driver
FOXA1 reports
Gene details
FOXA1 |
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Ensembl ID
ENSG00000129514
Transcript ID ENST00000250448 Protein ID ENSP00000250448 |
Cancer types where is driver
2
Cohorts where is driver 15 Mutated samples 224 Mutations 305 |
Mode of action Loss of function |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
BRCA (Breast adenocarcinoma) | 61 | 49 | 80.33 |
PRAD (Prostate adenocarcinoma) | 90 | 74 | 82.22 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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