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FLT3 is detected as a mutational cancer driver

FLT3 reports

Gene details
FLT3
Ensembl ID ENSG00000122025
Transcript ID ENST00000241453
Protein ID ENSP00000241453
Cancer types where is driver 2
Cohorts where is driver 7
Mutated samples 48
Mutations 415
Mode of action Activating
Known driver True
Method signals per Cancer Type
Cancer type Methods Samples Samples (%)
ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination
Observed mutations in tumors
The mutations needle plot shows the distribution of the observed mutations along the protein sequence.
Mutation (GRCh38) Protein Position Samples Consequence