FBXW7 is detected as a mutational cancer driver
FBXW7 reports
Gene details
FBXW7 |
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Ensembl ID
ENSG00000109670
Transcript ID ENST00000603548 Protein ID ENSP00000474725 |
Cancer types where is driver
16
Cohorts where is driver 33 Mutated samples 433 Mutations 656 |
Mode of action Loss of function |
Known driver True |
Method signals per Cancer Type
Cancer type | Methods | Samples | Samples (%) |
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In-silico saturation mutagenesis
Model | Mutations | Driver mutations | Driver mutations (%) |
---|---|---|---|
COREAD (Colorectal adenocarcinoma) | 90 | 72 | 80.00 |
UCEC (Endometrial cancer) | 30 | 29 | 96.67 |
Observed mutations in tumors
Mutation (GRCh38) | Protein Position | Samples | Consequence |
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