IntOGen - FBXO11 gene cancer mutations

FBXO11 is detected as a mutational cancer driver

FBXO11 reports

Methods
Mutation distribution

Gene details

FBXO11
Ensembl ID ENSG00000138081 Transcript ID ENST00000403359 Protein ID ENSP00000384823
Cancer types where is driver 2 Cohorts where is driver 2 Mutated samples 17 Mutations 214
Mode of action Loss of function
Known driver True

Method signals per Cancer Type

Cancer type	Methods	Samples	Samples (%)

ClustL HotMAPS smRegions Clustered Mutations
CBaSE dNdScv Recurrent Mutations
FML Functional Mutations
MutPanning Tri-nucleotide specific bias
combination Combination

The mutations needle plot shows the distribution of the observed mutations along the protein sequence.

Mutation (GRCh38)	Protein Position	Samples	Consequence